
WB analysis of human spleen (A), pig pancreas (B), (1ug/ml) mouse spleen (C) lysate and negative control HeLa (D) cell lysate using GTX89995 SOCS1 antibody, C-term. Dilution : 0.3microg/ml Loading : 35microg protein in RIPA buffer
SOCS1 antibody, C-term
GTX89995
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Porcine
TargetSOCS1
Overview
- SupplierGeneTex
- Product NameSOCS1 antibody, C-term
- Delivery Days Customer7
- Application Supplier NoteWB: 0.1-1microg/ml. FACS: 10microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID8651
- Target nameSOCS1
- Target descriptionsuppressor of cytokine signaling 1
- Target synonymsAISIMD; CIS1; CISH1; cytokine-inducible SH2 protein 1; JAB; JAK binding protein; SOCS-1; SSI1; SSI-1; STAT induced SH3 protein 1; STAT-induced STAT inhibitor 1; suppressor of cytokine signaling 1; Tec-interacting protein 3; TIP3; TIP-3
- HostGoat
- IsotypeIgG
- Protein IDO15524
- Protein NameSuppressor of cytokine signaling 1
- Scientific DescriptionThis gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse, Porcine
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203