SOCS3 antibody [C2C3], C-term

GeneTex

SOCS3 antibody [C2C3], C-term

9

WB: 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

1.42 mg/ml

Unconjugated

SOCS3

suppressor of cytokine signaling 3

ATOD4; CIS3; Cish3; cytokine-inducible SH2 protein 3; SOCS-3; SSI3; SSI-3; STAT-induced STAT inhibitor 3; suppressor of cytokine signaling 3

Rabbit

IgG

Suppressor of cytokine signaling 3

This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq, Jul 2008]

-20°C,2°C to 8°C

12352203