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Somatostatin antibody [YC7]

GTX39061
GeneTex
ApplicationsImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityGuinea Pig, Human, Mouse, Porcine, Rat, Zebra Fish
TargetSST
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Overview

  • Supplier
    GeneTex
  • Product Name
    Somatostatin antibody [YC7]
  • Delivery Days Customer
    9
  • Antibody Specificity
    The epitope recognised by this antibody lies within the 1-14 amino acid sequence of cyclic somatostatin.
  • Applications
    ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    YC7
  • Conjugate
    Unconjugated
  • Gene ID6750
  • Target name
    SST
  • Target description
    somatostatin
  • Target synonyms
    growth hormone release-inhibiting factor; prepro-somatostatin; SMST; somatostatin; somatostatin-14; somatostatin-28; SST1
  • Host
    Rat
  • Isotype
    IgG2b
  • Protein IDP61278
  • Protein Name
    Somatostatin
  • Scientific Description
    The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. [provided by RefSeq, Jul 2008]
  • Reactivity
    Guinea Pig, Human, Mouse, Porcine, Rat, Zebra Fish
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Decoding pancreatic endocrine cell differentiation and beta cell regeneration in zebrafish.
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  • Transplantation of insulin-producing cells derived from human mesenchymal stromal/stem cells into diabetic humanized mice.
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  • Neuromedin U suppresses glucose-stimulated insulin secretion in pancreatic beta cells. Zhang W et al., 2017 Nov 4, Biochem Biophys Res Commun
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  • Hes3 is expressed in the adult pancreatic islet and regulates gene expression, cell growth, and insulin release. Masjkur J et al., 2014 Dec 19, J Biol Chem
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