Sorafenib
S7397
CAS Number284461-73-0
Product group Chemicals
Estimated Purity...
Overview
- SupplierSelleck Chemicals
- Product NameSorafenib [284461-73-0]
- Delivery Days Customer9
- CAS Number284461-73-0
- CertificationResearch Use Only
- Estimated Purity...
- Scientific DescriptionSorafenib is a multikinase inhibitor of Raf-1 and B-Raf with IC50 of 6 nM and 22 nM in cell-free assays, respectively. Sorafenib inhibits VEGFR-2, VEGFR-3, PDGFR-beta, Flt-3 and c-KIT with IC50 of 90 nM, 20 nM, 57 nM, 59 nM and 68 nM, respectively. Sorafenib induces autophagy and apoptosis and activates ferroptosis with anti-tumor activity.
- Storage Instruction-80°C
- UNSPSC51202000