Sorafenib (BAY 43-9006)
M3026
CAS Number284461-73-0
Product group Chemicals
Molecular Weight464.82
Overview
- SupplierAbMole BioScience
- Product NameSorafenib (BAY 43-9006)
- Delivery Days Customer9
- CAS Number284461-73-0
- CertificationResearch Use Only
- Molecular FormulaC21H16ClF3N4O3
- Molecular Weight464.82
- Scientific DescriptionSorafenib (BAY 43-9006) is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively. Sorafenib is a multikinase inhibitor with IC50 values of 15 nM, 20 nM, 57 nM and 58 nM for VEGFR3, PDGFRbèta, FLT3 and c-Kit, respectively. Sorafenib induces autophagy and apoptosis. Sorafenib is a ferroptosis activator.
- SMILESCNC(=O)C1=CC(=CC=N1)OC2=CC=C(NC(=O)NC3=CC=C(Cl)C(=C3)C(F)(F)F)C=C2
- UNSPSC12352200
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