ICC/IF analysis of PANC-1 cells using GTX83063 SorLA antibody [3B6B11]. Green : SorLA Blue: DRAQ5 fluorescent DNA dye Red: Actin filaments
![IHC-P analysis of human cerebrum tissue using GTX83063 SorLA antibody [3B6B11].](https://www.genetex.com/upload/website/prouct_img/normal/GTX83063/GTX83063_20170912_IHC-P_1_w_23061322_408.webp "IHC-P analysis of human cerebrum tissue using GTX83063 SorLA antibody [3B6B11].")
![IHC-P analysis of human brain, cortex tissue using GTX83063 SorLA antibody [3B6B11].](https://www.genetex.com/upload/website/prouct_img/normal/GTX83063/GTX83063_20170912_IHC-P_w_23061322_121.webp "IHC-P analysis of human brain, cortex tissue using GTX83063 SorLA antibody [3B6B11].")
![WB analysis of truncated SorLA recombinant protein using GTX83063 SorLA antibody [3B6B11].](https://www.genetex.com/upload/website/prouct_img/normal/GTX83063/GTX83063_20170912_WB_w_23061322_402.webp "WB analysis of truncated SorLA recombinant protein using GTX83063 SorLA antibody [3B6B11].")
ICC/IF analysis of PANC-1 cells using GTX83063 SorLA antibody [3B6B11]. Green : SorLA Blue: DRAQ5 fluorescent DNA dye Red: Actin filaments
SorLA antibody [3B6B11]
GTX83063
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetSORL1
Overview
- SupplierGeneTex
- Product NameSorLA antibody [3B6B11]
- Delivery Days Customer9
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID3B6B11
- ConjugateUnconjugated
- Gene ID6653
- Target nameSORL1
- Target descriptionsortilin related receptor 1
- Target synonymsC11orf32; gp250; LDLR relative with 11 ligand-binding repeats; low-density lipoprotein receptor relative with 11 ligand-binding repeats; LR11; LRP9; mosaic protein LR11; SORLA; SorLA-1; sortilin-related receptor; sortilin-related receptor, L(DLR class) A repeats containing; sorting protein-related receptor containing LDLR class A repeats
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThis gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10) domain-containing receptor family, and the low density lipoprotein receptor (LDLR) family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded protein is translated as a preproprotein and likely plays roles in endocytosis and sorting. There may be an association between expression of this locus and Alzheimers Disease.[provided by RefSeq, Sep 2010]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- Presenilin1 inhibits glioblastoma cell invasiveness via promoting Sortilin cleavage. Yang W et al., 2021 Nov 15, Cell Commun SignalRead more