SorLA antibody [C3], C-term

GeneTex

SorLA antibody [C3], C-term

9

Western Blot

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

SORL1

sortilin related receptor 1

C11orf32; gp250; LDLR relative with 11 ligand-binding repeats; low-density lipoprotein receptor relative with 11 ligand-binding repeats; LR11; LRP9; mosaic protein LR11; SORLA; SorLA-1; sortilin-related receptor; sortilin-related receptor, L(DLR class) A repeats containing; sorting protein-related receptor containing LDLR class A repeats

Rabbit

IgG

Sortilin-related receptor

This gene encodes a protein that belongs to the families of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins, of low density lipoprotein receptor (LDLR) proteins, and of fibronectin type III repeats proteins. In addition to VPS10, LDLR and fibronectin type 3 domains, this protein also includes an epidermal growth factor precursor-like module, a single transmembrane segment and a cytoplasmic tail with features similar to endocytosis- and sorting-competent receptors. Members of the VPS10 domain-containing receptor family are large with many exons but the CDS lengths are usually less than 3700 nt; this gene is an exception to the pattern with a CDS length greater than 6600 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. The encoded protein is mainly intracellular and localizes in the paranuclear compartment. It is synthesized as a preproprotein, and when the propeptide is still attached, no binding occurs to the VPS10 domain. This gene is strongly expressed in the central nervous system. [provided by RefSeq]

-20°C or -80°C,2°C to 8°C

12352203