Sotrastaurin [425637-18-9]

MedChem Express

Sotrastaurin [425637-18-9]

10

425637-18-9

Research Use Only

99.71

C25H22N6O2

438.48

Sotrastaurin (AEB071) is a potent and orally-active pan-PKC inhibitor, with Kis of 0.22 nM, 0.64 nM, 0.95 nM, 1.8 nM, 2.1 nM and 3.2 nM for PKCtheta, PKCbeta, PKCalpha, PKCeta, PKCdelta and PKCepsilon, respectively[1].

O=C(C(C1=C2C=CC=CC2=NC(N3CCN(C)CC3)=N1)=C4C5=CNC6=C5C=CC=C6)NC4=O

-20°C,2°C to 8°C

12352200