Sotrastaurin

AbMole BioScience

Sotrastaurin

9

425637-18-9

Chemical

Research Use Only

>98%

C25H22N6O2

438.48

Sotrastaurin is a potent and orally-active pan-PKC inhibitor, with Kis of 0.22 nM, 0.64nM, 0.95 nM, 1.8 nM, 2.1 nM and 3.2 nM for PKCthèta, PKCbèta, PKCalfa, PKCèta, PKCdelta and PKCepsilon, respectively.

CN1CCN(CC1)C2=NC(=C3C=CC=CC3=N2)C4=C(C(=O)NC4=O)C5=C[NH]C6=C5C=CC=C6

12352200