SP100 Polyclonal Antibody

Reddot Biotech

SP100 Polyclonal Antibody

5

1 mg/ml

SP100

SP100 nuclear antigen

lysp100b; nuclear autoantigen Sp-100; nuclear dot-associated Sp100 protein; SP100-HMG nuclear autoantigen; speckled 100 kDa

This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein.

-20°C

12352203