SPN Antibody

Cusabio

SPN Antibody

20

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

SPN

sialophorin

CD43; galactoglycoprotein; GALGP; GPL115; leukocyte sialoglycoprotein; leukosialin; LSN; sialophorin (gpL115, leukosialin, CD43)

Rabbit

IgG

Leukosialin

One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response .

Human

-20°C or -80°C

41116161