WB analysis of human small intestine tissue lysate using GTX85025 SPRED2 antibody. Working concentration : (A) 1 and (B) 2 microg/ml
WB analysis of human small intestine tissue lysate using GTX85025 SPRED2 antibody. Working concentration : (A) 1 and (B) 2 microg/ml
SPRED2 antibody
GTX85025
Overview
- SupplierGeneTex
- Product NameSPRED2 antibody
- Delivery Days Customer9
- Antibody SpecificityThis Spred2 antibody is predicted to have no cross-reactivity to Spred1 or Spred3.
- Application Supplier NoteWB: 1 - 2 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- Concentration1 mg/ml
- FormulationLiquid
- Gene ID200734
- Target nameSPRED2
- Target descriptionsprouty related EVH1 domain containing 2
- Target synonymsSpred-2; sprouty protein with EVH-1 domain 2, related sequence; sprouty-related, EVH1 domain-containing protein 2
- Protein IDQ7Z698
- Protein NameSprouty-related, EVH1 domain-containing protein 2
- Scientific DescriptionSpred2 is a member of the Sprouty family, a group of proteins that act as negative regulators during development. Like Spred1, Spred2 acts by suppressing the phosphorylation and activation of Raf. The Spred proteins have also been implicated in the negative feedback regulation of FGF signaling in embryogenesis and angiogenesis. Further studies have shown that expression levels of Spred1 and Spred2 proteins are inversely correlated with the incidence of tumor invasion and metastasis in human hepatocellular carcinoma (HHC), suggesting that these proteins could be useful as prognostic factors and therapeutic targets in HCC. At least two isoforms of Spred2 are known to exist. This Spred2 antibody is predicted to have no cross-reactivity to Spred1 or Spred3.
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203