SR-717 (free acid) [2375420-34-9]

MedChem Express

SR-717 (free acid) [2375420-34-9]

10

2375420-34-9

Research Use Only

98.05

C15H9F2N5O3

345.26

SR-717 free acid is a non-nucleotide STING agonist with EC50s of 2.1 microM and 2.2 microM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. SR-717 free acid is a stable cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) mimetic. Antitumor activity[1].

O=C(O)C1=CC(F)=C(F)C=C1NC(C2=NN=C(N3C=CN=C3)C=C2)=O

-20°C,2°C to 8°C

12352200