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SR-BI antibody

GTX113645
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetSCARB1
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Overview

  • Supplier
    GeneTex
  • Product Name
    SR-BI antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.12 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID949
  • Target name
    SCARB1
  • Target description
    scavenger receptor class B member 1
  • Target synonyms
    CD36 and LIMPII analogous 1; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1; CD36L1; CLA1; CLA-1; HDLQTL6; scavenger receptor class B member 1; scavenger receptor class B type III; SRB1; SR-BI
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ8WTV0
  • Protein Name
    Scavenger receptor class B member 1
  • Scientific Description
    Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Probable receptor for HDL, located in particular region of the plasma membrane, called caveolae. Facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. Receptor for hepatitis C virus glycoprotein E2. Binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. Plays an important role in the uptake of HDL cholesteryl ester.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • The LOX-1 receptor ectopically expressed in the liver alleviates atherosclerosis by clearing Ox-LDL from the circulation. Wang Z et al., 2022 Mar 2, Mol Med
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  • Combination of apolipoprotein A1-modi liposome-doxorubicin with autophagy inhibitors overcame drug resistance in vitro. Wang B et al., 2014 Dec, J Pharm Sci
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  • Completion of the entire hepatitis C virus life cycle in genetically humanized mice. Dorner M et al., 2013 Sep 12, Nature
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