SR-BI antibody
GTX113645
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetSCARB1
Overview
- SupplierGeneTex
- Product NameSR-BI antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.12 mg/ml
- ConjugateUnconjugated
- Gene ID949
- Target nameSCARB1
- Target descriptionscavenger receptor class B member 1
- Target synonymsCD36 and LIMPII analogous 1; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1; CD36L1; CLA1; CLA-1; HDLQTL6; scavenger receptor class B member 1; scavenger receptor class B type III; SRB1; SR-BI
- HostRabbit
- IsotypeIgG
- Protein IDQ8WTV0
- Protein NameScavenger receptor class B member 1
- Scientific DescriptionReceptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Probable receptor for HDL, located in particular region of the plasma membrane, called caveolae. Facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. Receptor for hepatitis C virus glycoprotein E2. Binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. Plays an important role in the uptake of HDL cholesteryl ester.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- The LOX-1 receptor ectopically expressed in the liver alleviates atherosclerosis by clearing Ox-LDL from the circulation. Wang Z et al., 2022 Mar 2, Mol MedRead more
- Combination of apolipoprotein A1-modi liposome-doxorubicin with autophagy inhibitors overcame drug resistance in vitro. Wang B et al., 2014 Dec, J Pharm SciRead more
- Completion of the entire hepatitis C virus life cycle in genetically humanized mice. Dorner M et al., 2013 Sep 12, NatureRead more