WB analysis of untreated (first lane) and TGF-bl-treated (second lane) primary cultured human lung fibroblast lysate using GTX88384 SRF antibody, Internal. Dilution : 1microg/ml
WB analysis of untreated (first lane) and TGF-bl-treated (second lane) primary cultured human lung fibroblast lysate using GTX88384 SRF antibody, Internal. Dilution : 1microg/ml
SRF antibody, Internal
GTX88384
Overview
- SupplierGeneTex
- Product NameSRF antibody, Internal - Orthogonal Validated
- Delivery Days Customer9
- Application Supplier NoteWB: 1-3microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID6722
- Target nameSRF
- Target descriptionserum response factor
- Target synonymsc-fos serum response element-binding transcription factor; MCM1; minichromosome maintenance 1 homolog; serum response factor
- HostGoat
- IsotypeIgG
- Protein IDP11831
- Protein NameSerum response factor
- Scientific DescriptionThis gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203