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SSB antibody

Research Use Only
GTX113555
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetSSB
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Overview

  • Supplier
    GeneTex
  • Product Name
    SSB antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.52 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID6741
  • Target name
    SSB
  • Target description
    small RNA binding exonuclease protection factor La
  • Target synonyms
    autoantigen La; La; la autoantigen; La ribonucleoprotein domain family, member 3; La/SSB; LARP3; lupus La antigen; lupus La protein; sjoegren syndrome type B antigen; Sjogren syndrome antigen B; SS-B; SS-B/La protein
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP05455
  • Protein Name
    Lupus La protein
  • Scientific Description
    La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III (see MIM 606007)-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome (MIM 270150) and systemic lupus erythematosus (SLE; MIM 152700) (Teplova et al., 2006 [PubMed 16387655]).[supplied by OMIM]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Regulation of hepatitis C virus translation initiation by iron: role of eIF3 and La protein. Wang Q et al., 2012 Aug, Virus Res
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