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STAMBP Antibody, Biotin conjugated

CSB-PA022794HD01HU
Cusabio
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetSTAMBP
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Overview

  • Supplier
    Cusabio
  • Product Name
    STAMBP Antibody, Biotin conjugated
  • Delivery Days Customer
    20
  • Applications
    ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Biotin
  • Gene ID10617
  • Target name
    STAMBP
  • Target description
    STAM binding protein
  • Target synonyms
    AMSH; associated molecule with the SH3 domain of STAM; endosome-associated ubiquitin isopeptidase; MICCAP; STAM-binding protein; testicular secretory protein Li 54
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO95630
  • Protein Name
    STAM-binding protein
  • Scientific Description
    Zinc metalloprotease that specifically cleaves \Lys-63\-linked polyubiquitin chains. Does not cleave \Lys-48\-linked polyubiquitin chains.Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes. Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization .Involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203