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STAT2 antibody [C2C3], C-term

GTX103117
GeneTex
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetSTAT2
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Overview

  • Supplier
    GeneTex
  • Product Name
    STAT2 antibody [C2C3], C-term
  • Delivery Days Customer
    9
  • Antibody Specificity
    IP/MS validation was supported by references (PMID:30377386)
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6773
  • Target name
    STAT2
  • Target description
    signal transducer and activator of transcription 2
  • Target synonyms
    IMD44; interferon alpha induced transcriptional activator; ISGF-3; P113; PTORCH3; signal transducer and activator of transcription 2; signal transducer and activator of transcription 2, 113kDa; STAT113
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP52630
  • Protein Name
    Signal transducer and activator of transcription 2
  • Scientific Description
    The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Loss of FLCN-FNIP1/2 induces a non-canonical interferon response in human renal tubular epithelial cells. Glykofridis IE et al., 2021 Jan 18, Elife
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  • A high-throughput pipeline for validation of antibodies. Sikorski K et al., 2018 Nov, Nat Methods
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  • miR-30a Remodels Subcutaneous Adipose Tissue Inflammation to Improve Insulin Sensitivity in Obesity. Koh EH et al., 2018 Dec, Diabetes
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  • Schisandrin A inhibits dengue viral replication via upregulating antiviral interferon responses through STAT signaling pathway. Yu JS et al., 2017 Mar 24, Sci Rep
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