Staurosporine

MedChem Express

Staurosporine [62996-74-1]

10

62996-74-1

99.98

C28H26N4O3

466.53

Staurosporine is a potent, ATP-competitive and non-selective inhibitor of protein kinases with IC 50 s of 6 nM, 15 nM, 2 nM, and 3 nM for PKC , PKA , c-Fgr , and Phosphorylase kinase respectively. Staurosporine also inhibits TAOK2 with an IC 50 of 3 microM. Staurosporine is an apoptosis inducer [1] [2] [3] [4] [5] .

O=C(NC1)C2=C1C3=C(C4=C2C5=C(C=CC=C5)N4[C@H]6C[C@@H](NC)[C@@H](OC)[C@]7(C)O6)N7C8=CC=CC=C83

-20°C,2°C to 8°C

12352200