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Chemical Structure
Chemical Structure
Chemical Structure

Staurosporine [62996-74-1]

Research Use Only
AG-CN2-0022
AdipoGen Life Sciences
CAS Number62996-74-1
Product group Chemicals
Estimated Purity>98%
Molecular Weight466.5
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Staurosporine
  • Delivery Days Customer
    10
  • CAS Number
    62996-74-1
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Hazard Information
    Danger
  • Molecular Formula
    C28H26N4O3
  • Molecular Weight
    466.5
  • Scientific Description
    Antibiotic. Antifungal and anti-yeast activity [1]. Inhibits platelet aggregation induced by collagen or ADP. Has no effect on thrombin-induced platelet aggregation [2]. Potent, cell permeable, reversible, ATP-competitive and broad spectrum inhibitor of protein kinases. Inhibits protein kinase A, CaM kinase, myosin light chain kinase, protein kinase C, protein kinase G, CDK1/cyclin B, CDK2/cyclin A, CDK4/cyclin D, CDK5/p25, GSK-3beta and Pim-1 kinase [3, 4, 5, 6, 12]. DYRK1A inhibitor (IC50=20nM) [13]. Key apoptosis inducer [7, 8, 10, 11]. Topoisomerase II (Topo II) inhibitor [9]. - Chemical. CAS: 62996-74-1. Formula: C28H26N4O3. MW: 466.5. Isolated from Streptomyces spiralis. Antibiotic. Antifungal and anti-yeast activity. Inhibits platelet aggregation induced by collagen or ADP. Has no effect on thrombin-induced platelet aggregation. Potent, cell permeable, reversible, ATP-competitive and broad spectrum inhibitor of protein kinases. Inhibits protein kinase A, CaM kinase, myosin light chain kinase, protein kinase C, protein kinase G, CDK1/cyclin B, CDK2/cyclin A, CDK4/cyclin D, CDK5/p25, GSK-3beta and Pim-1 kinase. Key apoptosis inducer. Topoisomerase II (Topo II) inhibitor.
  • SMILES
    [H][C@]12C[C@@H](NC)[C@@H](OC)[C@](C)(O1)N1C3=C(C=CC=C3)C3=C4CNC(=O)C4=C4C5=C(C=CC=C5)N2C4=C13
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200