
Chemical Structure
Staurosporine [62996-74-1]

AG-CN2-0022
Overview
- SupplierAdipoGen Life Sciences
- Product NameStaurosporine
- Delivery Days Customer10
- CAS Number62996-74-1
- CertificationResearch Use Only
- Estimated Purity>98%
- Hazard InformationDanger
- Molecular FormulaC28H26N4O3
- Molecular Weight466.5
- Scientific DescriptionAntibiotic. Antifungal and anti-yeast activity [1]. Inhibits platelet aggregation induced by collagen or ADP. Has no effect on thrombin-induced platelet aggregation [2]. Potent, cell permeable, reversible, ATP-competitive and broad spectrum inhibitor of protein kinases. Inhibits protein kinase A, CaM kinase, myosin light chain kinase, protein kinase C, protein kinase G, CDK1/cyclin B, CDK2/cyclin A, CDK4/cyclin D, CDK5/p25, GSK-3beta and Pim-1 kinase [3, 4, 5, 6, 12]. DYRK1A inhibitor (IC50=20nM) [13]. Key apoptosis inducer [7, 8, 10, 11]. Topoisomerase II (Topo II) inhibitor [9]. - Chemical. CAS: 62996-74-1. Formula: C28H26N4O3. MW: 466.5. Isolated from Streptomyces spiralis. Antibiotic. Antifungal and anti-yeast activity. Inhibits platelet aggregation induced by collagen or ADP. Has no effect on thrombin-induced platelet aggregation. Potent, cell permeable, reversible, ATP-competitive and broad spectrum inhibitor of protein kinases. Inhibits protein kinase A, CaM kinase, myosin light chain kinase, protein kinase C, protein kinase G, CDK1/cyclin B, CDK2/cyclin A, CDK4/cyclin D, CDK5/p25, GSK-3beta and Pim-1 kinase. Key apoptosis inducer. Topoisomerase II (Topo II) inhibitor.
- SMILES[H][C@]12C[C@@H](NC)[C@@H](OC)[C@](C)(O1)N1C3=C(C=CC=C3)C3=C4CNC(=O)C4=C4C5=C(C=CC=C5)N2C4=C13
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200