STIP1 antibody
GTX103068
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetSTIP1
Overview
- SupplierGeneTex
- Product NameSTIP1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID10963
- Target nameSTIP1
- Target descriptionstress induced phosphoprotein 1
- Target synonymsepididymis secretory sperm binding protein Li 94n; HEL-S-94n; HOP; hsc70/Hsp90-organizing protein; Hsp70/Hsp90-organizing protein; IEF-SSP-3521; NY-REN-11 antigen; P60; renal carcinoma antigen NY-REN-11; STI1; STI1L; stress-induced-phosphoprotein 1; transformation-sensitive protein IEF SSP 3521
- HostRabbit
- IsotypeIgG
- Protein IDP31948
- Protein NameStress-induced-phosphoprotein 1
- Scientific DescriptionSTIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- JAK2-Mediated Phosphorylation of Stress-Induced Phosphoprotein-1 (STIP1) in Human Cells. Chao A et al., 2022 Feb 22, Int J Mol SciRead more
- N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting. Lin PH et al., 2015 Jun 24, J Biomed SciRead more
- Proteomic analysis of rhein-induced cyt: ER stress mediates cell death in breast cancer cells. Huang HJ et al., 2014 Dec, Mol BiosystRead more
- Hyaluronic acid-dependent protection against UVB-damaged human corneal cells. Li JM et al., 2013 Jul, Environ Mol MutagenRead more
- Hyaluronic acid-dependent protection in H9C2 cardiomyocytes: a cell model of heart ischemia-reperfusion injury and treatment. Law CH et al., 2013 Jan 7, ToxicologyRead more