STIP1 antibody
GTX103068
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetSTIP1
Overview
- SupplierGeneTex
- Product NameSTIP1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID10963
- Target nameSTIP1
- Target descriptionstress induced phosphoprotein 1
- Target synonymsHEL-S-94n, HOP, IEF-SSP-3521, P60, STI1, STI1L, stress-induced-phosphoprotein 1, Hsp70/Hsp90-organizing protein, NY-REN-11 antigen, epididymis secretory sperm binding protein Li 94n, hsc70/Hsp90-organizing protein, renal carcinoma antigen NY-REN-11, transformation-sensitive protein IEF SSP 3521
- HostRabbit
- IsotypeIgG
- Protein IDP31948
- Protein NameStress-induced-phosphoprotein 1
- Scientific DescriptionSTIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Chao A, Liao MJ, Chen SH, et al. JAK2-Mediated Phosphorylation of Stress-Induced Phosphoprotein-1 (STIP1) in Human Cells. Int J Mol Sci. 2022,23(5). doi: 10.3390/ijms23052420Read this paper
- Lin PH, Lin HY, Kuo CC, et al. N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting. J Biomed Sci. 2015,22(1):44. doi: 10.1186/s12929-015-0152-0Read this paper
- Huang HJ, Lin CC, Chou HC, et al. Proteomic analysis of rhein-induced cyt: ER stress mediates cell death in breast cancer cells. Mol Biosyst. 2014,10(12):3086-100. doi: 10.1039/c4mb00451eRead this paper
- Li JM, Chou HC, Wang SH, et al. Hyaluronic acid-dependent protection against UVB-damaged human corneal cells. Environ Mol Mutagen. 2013,54(6):429-49. doi: 10.1002/em.21794Read this paper
- Law CH, Li JM, Chou HC, et al. Hyaluronic acid-dependent protection in H9C2 cardiomyocytes: a cell model of heart ischemia-reperfusion injury and treatment. Toxicology. 2013,303:54-71. doi: 10.1016/j.tox.2012.11.006Read this paper
Datasheet
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