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STIP1 antibody

GTX103068
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetSTIP1
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Overview

  • Supplier
    GeneTex
  • Product Name
    STIP1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID10963
  • Target name
    STIP1
  • Target description
    stress induced phosphoprotein 1
  • Target synonyms
    epididymis secretory sperm binding protein Li 94n; HEL-S-94n; HOP; hsc70/Hsp90-organizing protein; Hsp70/Hsp90-organizing protein; IEF-SSP-3521; NY-REN-11 antigen; P60; renal carcinoma antigen NY-REN-11; STI1; STI1L; stress-induced-phosphoprotein 1; transformation-sensitive protein IEF SSP 3521
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP31948
  • Protein Name
    Stress-induced-phosphoprotein 1
  • Scientific Description
    STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • JAK2-Mediated Phosphorylation of Stress-Induced Phosphoprotein-1 (STIP1) in Human Cells. Chao A et al., 2022 Feb 22, Int J Mol Sci
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  • N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting. Lin PH et al., 2015 Jun 24, J Biomed Sci
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  • Proteomic analysis of rhein-induced cyt: ER stress mediates cell death in breast cancer cells. Huang HJ et al., 2014 Dec, Mol Biosyst
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  • Hyaluronic acid-dependent protection against UVB-damaged human corneal cells. Li JM et al., 2013 Jul, Environ Mol Mutagen
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  • Hyaluronic acid-dependent protection in H9C2 cardiomyocytes: a cell model of heart ischemia-reperfusion injury and treatment. Law CH et al., 2013 Jan 7, Toxicology
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