Western Blot Positive WB detected in: Hela whole cell lysate, A375 whole cell lysate, HepG2 whole cell lysate All lanes: STK24 antibody at 3microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 50, 48 kDa Observed band size: 50 kDa
STK24 Antibody
CSB-PA00249A0RB
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetSTK24
Overview
- SupplierCusabio
- Product NameSTK24 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID8428
- Target nameSTK24
- Target descriptionserine/threonine kinase 24
- Target synonymsepididymis secretory protein Li 95; HEL-S-95; mammalian STE20-like protein kinase 3; MST3; MST3B; serine/threonine kinase 24 (STE20 homolog, yeast); serine/threonine-protein kinase 24; STE20; STE20-like kinase 3; STE20-like kinase MST3; sterile 20-like kinase 3; STK3
- HostRabbit
- IsotypeIgG
- Protein IDQ9Y6E0
- Protein NameSerine/threonine-protein kinase 24
- Scientific DescriptionSerine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on \\\Thr-442\\\ and stimulates its kinase activity. Regulates cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphorylation through PTPN12. May act as a key regulator of axon regeneration in the optic nerve and radial nerve.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203