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Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA892131ESR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA892131ESR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA892131ESR1HU at dilution of 1:100

STOML2 Antibody

CSB-PA892131ESR1HU
Cusabio
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
TargetSTOML2
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Overview

  • Supplier
    Cusabio
  • Product Name
    STOML2 Antibody
  • Delivery Days Customer
    20
  • Applications
    ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID30968
  • Target name
    STOML2
  • Target description
    stomatin like 2
  • Target synonyms
    EPB72-like 2; EPB72-like protein 2; HSPC108; paraprotein target 7; paratarg-7; SLP-2; stomatin (EPB72)-like 2; stomatin-like protein 2, mitochondrial
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9UJZ1
  • Protein Name
    Stomatin-like protein 2, mitochondrial
  • Scientific Description
    Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins including prohibitin and may therefore act in the organization of functional microdomains in mitochondrial membranes. Through regulation of the mitochondrial function may play a role into several biological processes including cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress. May play a role in calcium homeostasis through negative regulation of calcium efflux from mitochondria. Required for mitochondrial hyperfusion a pro-survival cellular response to stress which results in increased ATP production by mitochondria. May also regulate the organization of functional domains at the plasma membrane and play a role in T-cell activation through association with the T-cell receptor signaling complex and its regulation.
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203

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Figure 1. Western blot analysis of STOML2 using anti-STOML2 antibody (M04108-1). Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30 ug of sample under reducing conditions. Lane 1: human Jurkat whole cell lysates, Lane 2: human Hela whole cell lysates, Lane 3: human Caco-2 whole cell lysates, Lane 4: human A549 whole cell lysates, Lane 5: rat brain tissue lysates, Lane 6: rat C6 whole cell lysates, Lane 7: mouse brain tissue lysates, Lane 8: mouse RAW264.7 whole cell lysates. After electrophoresis, proteins were transferred to a nitrocellulose membrane at 150 mA for 50-90 minutes. Blocked the membrane with 5% non-fat milk/TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-STOML2 antigen affinity purified monoclonal antibody (M04108-1) at 1:500 overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:500 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for STOML2 at approximately 39 kDa. The expected band size for STOML2 is at 39 kDa.
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