Bio-Connect

SU16f

HY-108628
MedChem Express
CAS Number251356-45-3
Product group Chemicals
Estimated Purity99.09
Molecular Weight386.44
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Overview

  • Supplier
    MedChem Express
  • Product Name
    SU16f [251356-45-3]
  • Delivery Days Customer
    9
  • CAS Number
    251356-45-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.09
  • Molecular Formula
    C24H22N2O3
  • Molecular Weight
    386.44
  • Scientific Description
    SU16f is a potent and selective PDGFRbeta inhibitor with IC 50 s of 10 nM, 140 nM, 2.29 microM for PDGFRbeta, PDGFR1, PDGFR2, respectively [1] . Neutralization of PDGFRbeta receptor by SU16f blocks the promoting role of GC-MSCs (gastric cancer-derived mesenchymal stem cells) conditioned medium in gastric cancer cell proliferation and migration [2] .
  • SMILES
    O=C(O)CCC1=C(C)NC(/C=C2C(NC3=C\2C=CC(C4=CC=CC=C4)=C3)=O)=C1C
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200