SU16f [251356-45-3]

TargetMol Chemicals

SU16f [251356-45-3]

4

251356-45-3

Chemical

Research Use Only

SU16f

98.38%

C24H22N2O3

386.44

SU16f (3-substituted indolin-2-one 16f) is a potent and selective PDGFRbeta inhibitor (IC50s: 10 nM, 140 nM, 2.29 microM for PDGFRbeta, PDGFR1, PDGFR2, respectively). Neutralization of PDGFRbeta receptor by SU16f blocks the promoting role of GC-MSCs conditioned medium in gastric cancer cell proliferation and migration.

3 years

C(=C1C=2C(=CC(=CC2)C3=CC=CC=C3)NC1=O)C4=C(C)C(CCC(O)=O)=C(C)N4

-20°C

12352200