SURF1 Polyclonal Antibody

Reddot Biotech

SURF1 Polyclonal Antibody

5

ImmunoHistoChemistry

Research Use Only

1 mg/ml

Unconjugated

SURF1

SURF1 cytochrome c oxidase assembly factor

CMT4K, MC4DN1, SHY1, surfeit locus protein 1, surfeit 1

Rabbit

IgG

This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency.

Human, Mouse, Rat

-20°C

12352203