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IHC-P analysis of human lung cancer tissue using GTX10584 Survivin antibody [32.1].
IHC-P analysis of human lung cancer tissue using GTX10584 Survivin antibody [32.1].
IHC-P analysis of human lung cancer tissue using GTX10584 Survivin antibody [32.1].

Survivin antibody [32.1]

GTX10584
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHamster, Human
TargetBIRC5
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Overview

  • Supplier
    GeneTex
  • Product Name
    Survivin antibody [32.1]
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody is specific for the nuclear form of survivin.
  • Application Supplier Note
    WB: 1:1000. ICC/IF: 1:10 - 1:500. IHC-P: 20 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    32.1
  • Concentration
    1.9 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID332
  • Target name
    BIRC5
  • Target description
    baculoviral IAP repeat containing 5
  • Target synonyms
    API4; apoptosis inhibitor 4; apoptosis inhibitor survivin; baculoviral IAP repeat-containing protein 5; EPR-1; survivin variant 3 alpha
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDO15392
  • Protein Name
    Baculoviral IAP repeat-containing protein 5
  • Scientific Description
    This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this genes expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq]
  • Reactivity
    Hamster, Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • The tyrosine kinase receptor RET interacts in vivo with aryl hydrocarbon receptor-interacting protein to alter survivin availability. Vargiolu M et al., 2009 Jul, J Clin Endocrinol Metab
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