![IHC-P analysis of human lung cancer tissue using GTX10584 Survivin antibody [32.1]. IHC-P analysis of human lung cancer tissue using GTX10584 Survivin antibody [32.1].](https://www.genetex.com/upload/website/prouct_img/normal/GTX10584/GTX10584_374_IHC-P_w_23060120_539.webp)
IHC-P analysis of human lung cancer tissue using GTX10584 Survivin antibody [32.1].
Survivin antibody [32.1]
GTX10584
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHamster, Human
TargetBIRC5
Overview
- SupplierGeneTex
- Product NameSurvivin antibody [32.1]
- Delivery Days Customer9
- Antibody SpecificityThis antibody is specific for the nuclear form of survivin.
- Application Supplier NoteWB: 1:1000. ICC/IF: 1:10 - 1:500. IHC-P: 20 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID32.1
- Concentration1.9 mg/ml
- ConjugateUnconjugated
- Gene ID332
- Target nameBIRC5
- Target descriptionbaculoviral IAP repeat containing 5
- Target synonymsAPI4; apoptosis inhibitor 4; apoptosis inhibitor survivin; baculoviral IAP repeat-containing protein 5; EPR-1; survivin variant 3 alpha
- HostMouse
- IsotypeIgG1
- Protein IDO15392
- Protein NameBaculoviral IAP repeat-containing protein 5
- Scientific DescriptionThis gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this genes expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq]
- ReactivityHamster, Human
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- The tyrosine kinase receptor RET interacts in vivo with aryl hydrocarbon receptor-interacting protein to alter survivin availability. Vargiolu M et al., 2009 Jul, J Clin Endocrinol MetabRead more