Syk antibody [SPM147]

GeneTex

Syk antibody [SPM147]

9

For IHC-P: Use at a dilution of 1-100 for 10 min. at RT. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. For IP: Use at a concentration of 2ug antibody/mg protein lysate. For WB: Use at a concentration of 1 microg/ml. Predicted molecular weight: 72 kDa. Optimal dilutions/concentrations should be determined by the researcher

ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

SPM147

0.2 mg/ml

Unconjugated

SYK

spleen associated tyrosine kinase

IMD82; p72-Syk; spleen tyrosine kinase; tyrosine-protein kinase SYK

Mouse

IgG2a

Tyrosine-protein kinase SYK

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

Human

2°C to 8°C

12352203