Syk Inhibitor II (dihydrochloride)

MedChem Express

Syk Inhibitor II (dihydrochloride) [227449-73-2]

10

227449-73-2

Research Use Only

C14H17Cl2F3N6O

413.23

Syk Inhibitor II dihydrochloride is a potent, high selective and ATP-competitive Syk inhibitor with an IC50 of 41 nM. Syk Inhibitor II dihydrochloride inhibits 5-HT release from RBL-cells with an IC50 of 460 nM. Syk Inhibitor II dihydrochloride shows less potent against other kinases and has anti-allergic effect[1].

O=C(C1=CN=C(NCCN)N=C1NC2=CC=CC(C(F)(F)F)=C2)N.[H]Cl.[H]Cl

12352200