SZL P1-41 [222716-34-9]

MedChem Express

SZL P1-41 [222716-34-9]

10

222716-34-9

Research Use Only

99.07

C24H24N2O3S

420.52

SZL P1-41 is a specific Skp2 inhibitor, binds to the F-box domain of Skp2 to prevent Skp1 association and Skp2 SCF complex formation. SZL P1-41, like Skp2 deficiency, augments p27-mediated apoptosis/senescence, while it impairs Akt-driven glycolysis. Anti-tumor activities[1][2].

O=C1C(C2=NC3=CC=CC=C3S2)=COC4=C(CN5CCCCC5)C(O)=C(CC)C=C14

-20°C,2°C to 8°C

12352200