SZL P1-41 [222716-34-9]
T3317
CAS Number222716-34-9
Product group Chemicals
Estimated Purity99.78%
Molecular Weight420.52
Overview
- SupplierTargetMol Chemicals
- Product NameSZL P1-41 [222716-34-9]
- Delivery Days Customer9
- CAS Number222716-34-9
- CertificationResearch Use Only
- Chemical NameSZL P1-41
- Estimated Purity99.78%
- Molecular FormulaC24H24N2O3S
- Molecular Weight420.52
- Scientific DescriptionSZL P1-41, a skp2 inhibitor, can prevent assembly of Skp2-Skp1 complexes. It selectively suppresses Skp2 SCF E3 ligase activity but exhibits no effect on the activity of other SCF complexes. It also inhibits Skp2-mediated p27 and Akt ubiquitination in vivo and in vitro. It suppresses the survival of Y cells and Y stem cells by triggering cell senescence and inhibiting glycolysis. It exhibits antitumor effects in multiple animal models and Y cell lines.
- Shelf life instruction3 years
- SMILESCCc1cc2c(occ(-c3nc4ccccc4s3)c2=O)c(CN2CCCCC2)c1O
- Storage Instruction-20°C
- UNSPSC12352200
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