FACS analysis of HL-60 cells using GTX82751 TAB2 antibody [3B5]. Green : TAB2 Purple : negative control
TAB2 antibody [3B5]
GTX82751
ApplicationsFlow Cytometry, Western Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetTAB2
Overview
- SupplierGeneTex
- Product NameTAB2 antibody [3B5]
- Delivery Days Customer9
- ApplicationsFlow Cytometry, Western Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID3B5
- ConjugateUnconjugated
- Gene ID23118
- Target nameTAB2
- Target descriptionTGF-beta activated kinase 1 (MAP3K7) binding protein 2
- Target synonymsCHTD2; MAP3K7IP2; mitogen-activated protein kinase kinase kinase 7-interacting protein 2; TAB-2; TAK1-binding protein 2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThe protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203