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FACS analysis of HL-60 cells using GTX82751 TAB2 antibody [3B5]. Green : TAB2 Purple : negative control
FACS analysis of HL-60 cells using GTX82751 TAB2 antibody [3B5]. Green : TAB2 Purple : negative control
FACS analysis of HL-60 cells using GTX82751 TAB2 antibody [3B5]. Green : TAB2 Purple : negative control

TAB2 antibody [3B5]

Research Use Only
GTX82751
GeneTex
ApplicationsFlow Cytometry, Western Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetTAB2
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Overview

  • Supplier
    GeneTex
  • Product Name
    TAB2 antibody [3B5]
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry, Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    3B5
  • Conjugate
    Unconjugated
  • Gene ID23118
  • Target name
    TAB2
  • Target description
    TGF-beta activated kinase 1 (MAP3K7) binding protein 2
  • Target synonyms
    CHTD2; MAP3K7IP2; mitogen-activated protein kinase kinase kinase 7-interacting protein 2; TAB-2; TAK1-binding protein 2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203