TAB2 antibody [3B5]

GeneTex

TAB2 antibody [3B5]

9

WB: 1/500 - 1/2000. FACS: 1/200 - 1/400. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Flow Cytometry, Western Blot, ELISA

Research Use Only

Monoclonal

3B5

Unconjugated

TAB2

TGF-beta activated kinase 1 (MAP3K7) binding protein 2

CHTD2; MAP3K7IP2; mitogen-activated protein kinase kinase kinase 7-interacting protein 2; TAB-2; TAK1-binding protein 2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

Mouse

IgG1

TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. [provided by RefSeq, Jul 2008]

Human

-20°C or -80°C,2°C to 8°C

12352203