Bio-Connect

TAF15 antibody, N-term

GTX77901
GeneTex
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityDrosophila, Human, Porcine
TargetTAF15
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Overview

  • Supplier
    GeneTex
  • Product Name
    TAF15 antibody, N-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 0.2-2.5 ug/ml. IHC-P: 2-10 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.5-1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID8148
  • Target name
    TAF15
  • Target description
    TATA-box binding protein associated factor 15
  • Target synonyms
    Npl3, RBP56, TAF2N, TAFII68, TATA-binding protein-associated factor 2N, RBP56/CSMF fusion, TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa, TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD (RNA-binding protein 56), TATA box-binding protein-associated factor 2N (RNA-binding protein 56), TBP-associated factor 15
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ92804
  • Protein Name
    TATA-binding protein-associated factor 2N
  • Scientific Description
    This gene encodes a member of the TET family of RNA-binding proteins. The encoded protein plays a role in RNA polymerase II gene transcription as a component of a distinct subset of multi-subunit transcription initiation factor TFIID complexes. Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene may play a role in amyotrophic lateral sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
  • Reactivity
    Drosophila, Human, Porcine
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Choi HJ, Joo Cha S, Do HA, et al. SCF-Slimb is critical for Glycogen synthase kinase-3β-mediated suppression of TAF15-induced neurotoxicity in Drosophila. J Neurochem. 2021,157(6):2119-2127. doi: 10.1111/jnc.15182
    Read this paper
  • Altanbyek V, Cha SJ, Kang GU, et al. Imbalance of mitochondrial dynamics in Drosophila models of amyotrophic lateral sclerosis. Biochem Biophys Res Commun. 2016,481(3-4):259-264. doi: 10.1016/j.bbrc.2016.10.134
    Read this paper
  • Blechingberg J, Holm IE, Nielsen AL. Characterization and expression analysis in the developing embryonic brain of the porcine FET family: FUS, EWS, and TAF15. Gene. 2012,493(1):27-35. doi: 10.1016/j.gene.2011.11.038
    Read this paper
  • Schatz N, Brändlein S, Rückl K, et al. Diagnostic and therapeutic potential of a human antibody cloned from a cancer patient that binds to a tumor-specific variant of transcription factor TAF15. Cancer Res. 2010,70(1):398-408. doi: 10.1158/0008-5472.CAN-09-2186
    Read this paper