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GTX77901 IHC-P Image
GTX77901 IHC-P Image
GTX77901 IHC-P Image

TAF15 antibody, N-term

Research Use Only
GTX77901
GeneTex
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityDrosophila, Human, Porcine
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    TAF15 antibody, N-term
  • Delivery Days Customer
    10
  • Applications
    ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.5-1 mg/ml
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a member of the TET family of RNA-binding proteins. The encoded protein plays a role in RNA polymerase II gene transcription as a component of a distinct subset of multi-subunit transcription initiation factor TFIID complexes. Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene may play a role in amyotrophic lateral sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
  • Reactivity
    Drosophila, Human, Porcine
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Characterization and expression analysis in the developing embryonic brain of the porcine FET family: FUS, EWS, and TAF15. Blechingberg J et al., 2012 Feb 1, Gene
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  • Diagnostic and therapeutic potential of a human antibody cloned from a cancer patient that binds to a tumor-specific variant of transcription factor TAF15. Schatz N et al., 2010 Jan 1, Cancer Res
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  • Imbalance of mitochondrial dynamics in Drosophila models of amyotrophic lateral sclerosis. Altanbyek V et al., 2016 Dec 9, Biochem Biophys Res Commun
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  • SCF-Slimb is critical for Glycogen synthase kinase-3beta-mediated suppression of TAF15-induced neurotoxicity in Drosophila. Choi HJ et al., 2021 Jun, J Neurochem
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