TAF15 antibody, N-term
GTX77901
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityDrosophila, Human, Porcine
TargetTAF15
Overview
- SupplierGeneTex
- Product NameTAF15 antibody, N-term
- Delivery Days Customer9
- Application Supplier NoteWB: 0.2-2.5 ug/ml. IHC-P: 2-10 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5-1 mg/ml
- ConjugateUnconjugated
- Gene ID8148
- Target nameTAF15
- Target descriptionTATA-box binding protein associated factor 15
- Target synonymsNpl3, RBP56, TAF2N, TAFII68, TATA-binding protein-associated factor 2N, RBP56/CSMF fusion, TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa, TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD (RNA-binding protein 56), TATA box-binding protein-associated factor 2N (RNA-binding protein 56), TBP-associated factor 15
- HostRabbit
- IsotypeIgG
- Protein IDQ92804
- Protein NameTATA-binding protein-associated factor 2N
- Scientific DescriptionThis gene encodes a member of the TET family of RNA-binding proteins. The encoded protein plays a role in RNA polymerase II gene transcription as a component of a distinct subset of multi-subunit transcription initiation factor TFIID complexes. Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene may play a role in amyotrophic lateral sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
- ReactivityDrosophila, Human, Porcine
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Choi HJ, Joo Cha S, Do HA, et al. SCF-Slimb is critical for Glycogen synthase kinase-3β-mediated suppression of TAF15-induced neurotoxicity in Drosophila. J Neurochem. 2021,157(6):2119-2127. doi: 10.1111/jnc.15182Read this paper
- Altanbyek V, Cha SJ, Kang GU, et al. Imbalance of mitochondrial dynamics in Drosophila models of amyotrophic lateral sclerosis. Biochem Biophys Res Commun. 2016,481(3-4):259-264. doi: 10.1016/j.bbrc.2016.10.134Read this paper
- Blechingberg J, Holm IE, Nielsen AL. Characterization and expression analysis in the developing embryonic brain of the porcine FET family: FUS, EWS, and TAF15. Gene. 2012,493(1):27-35. doi: 10.1016/j.gene.2011.11.038Read this paper
- Schatz N, Brändlein S, Rückl K, et al. Diagnostic and therapeutic potential of a human antibody cloned from a cancer patient that binds to a tumor-specific variant of transcription factor TAF15. Cancer Res. 2010,70(1):398-408. doi: 10.1158/0008-5472.CAN-09-2186Read this paper




