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TAK-242 (Resatorvid)

M4838
AbMole BioScience
CAS Number243984-11-4
Product group Chemicals
Molecular Weight361.82
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    TAK-242 (Resatorvid)
  • Delivery Days Customer
    9
  • CAS Number
    243984-11-4
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C15H17ClFNO4S
  • Molecular Weight
    361.82
  • Scientific Description
    Resatorvid (TAK-242) is a selective TLR4 signaling inhibitor. Resatorvid inhibited the production of NO, TNF-alfa and IL-6 with IC50 values of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid down-regulates the expression of MyD88 and TRIF signaling molecules downstream of TLR4. Resatorvid inhibits autophagy and plays a key role in a variety of inflammatory diseases.
  • SMILES
    CCOC(=O)C1=CCCCC1[S](=O)(=O)NC2=C(Cl)C=C(F)C=C2
  • UNSPSC
    12352200

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