TAK1 antibody

GeneTex

TAK1 antibody

9

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Polyclonal

1.06 mg/ml

Unconjugated

MAP3K7

mitogen-activated protein kinase kinase kinase 7

CSCF; FMD2; MEKK7; mitogen-activated protein kinase kinase kinase 7; TAK1; TGF1a; TGF-beta activated kinase 1; transforming growth factor-beta-activated kinase 1

Rabbit

IgG

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Human, Mouse, Rat

2°C to 8°C,-20°C or -80°C

12352203