WB analysis of HEK293 overexpressing human TAK1 with DYKDDDDK tag using GTX89337 TAK1 antibody, Internal. Lane A : primary antibody Lane B : Mock-transfected HEK293 probed with primary antibody Lane C : Tag antibody Dilution : 1microg/ml Loading : 10microg protein in RIPA buffer
TAK1 antibody, Internal
GTX89337
Overview
- SupplierGeneTex
- Product NameTAK1 antibody, Internal
- Delivery Days Customer9
- Antibody SpecificityThis antibody is expected to recognise isoform A (NP_003179.1) and isoform B (NP_663304.1).
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID6885
- Target nameMAP3K7
- Target descriptionmitogen-activated protein kinase kinase kinase 7
- Target synonymsCSCF; FMD2; MEKK7; mitogen-activated protein kinase kinase kinase 7; TAK1; TGF1a; TGF-beta activated kinase 1; transforming growth factor-beta-activated kinase 1
- HostGoat
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203