Talarozole

MedChem Express

Talarozole [201410-53-9]

10

201410-53-9

Research Use Only

99.61

C21H23N5S

377.51

Talarozole (R115866) is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA) which increases intracellular levels of endogenous all-trans retinoic acid (RA). Talarozole inhibits both CYP26A1 and CYP26B1 with IC 50 s of 5.4 and 0.46 nM, respectively.

CCC(CC)C(C1=CC=C(NC2=NC3=CC=CC=C3S2)C=C1)N4N=CN=C4

-20°C,2°C to 8°C

12352200