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Talarozole [201410-53-9]

Talarozole [201410-53-9]

T7370
TargetMol Chemicals
CAS Number201410-53-9
DownloadMSDS
Product group Chemicals
Estimated Purity≥95%
Molecular Weight377.51
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Talarozole [201410-53-9]
  • Delivery Days Customer
    4
  • CAS Number
    201410-53-9
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Talarozole
  • Estimated Purity
    ≥95%
  • Molecular Formula
    C21H23N5S
  • Molecular Weight
    377.51
  • Scientific Description
    Talarozole (R115866) is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA) that inhibits CYP26A1 and CYP26B1 with IC50s of 5.4 and 0.46 nM, respectively, for treating acne, psoriasis, and other keratinization disorders.
  • Shelf life instruction
    3 years
  • SMILES
    CCC(CC)C(c1ccc(Nc2nc3ccccc3s2)cc1)n1cncn1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Both all-trans retinoic acid and cytochrome P450 (CYP26) inhibitors affect the expression of vitamin A metabolizing enzymes and retinoid biomarkers in organotypic epidermis. Pavez Lori E et al., 2009 Aug, Arch Dermatol Res
    Read more

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