Tamoxifen (Citrate)

MedChem Express

Tamoxifen (Citrate) [54965-24-1]

10

54965-24-1

Research Use Only

99.93

C32H37NO8

563.64

Tamoxifen Citrate (ICI 46474) is an orally active, selective estrogen receptor modulator (SERM) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells[1][2][3].Tamoxifen Citrate is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen Citrate also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.1 microM and 1.8 microM, respectively[5]. Tamoxifen Citrate activates autophagy and induces apoptosis[4]. Tamoxifen Citrate also can induce gene knockout of CreER transgenic mouse[6].

CC/C(C1=CC=CC=C1)=C(C2=CC=C(OCCN(C)C)C=C2)\C3=CC=CC=C3.O=C(CC(C(O)=O)(O)CC(O)=O)O

2°C to 8°C

12352200