TAP2 antibody

GeneTex

TAP2 antibody

7

WB: 1:500 - 1:2000. ICC/IF: 1:50 - 1:200. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

Unconjugated

TAP2

transporter 2, ATP binding cassette subfamily B member

ABC18, ABCB3, APT2, D6S217E, MHC1D2, PSF-2, PSF2, RING11, antigen peptide transporter 2, ABC transporter, MHC 2, ATP-binding cassette, sub-family B (MDR/TAP), member 3, peptide supply factor 2, peptide transporter PSF2, peptide transporter involved in antigen processing 2, really interesting new gene 11 protein, transporter 2, ABC (ATP binding cassette), transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)

Rabbit

IgG

Antigen peptide transporter 2

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. [provided by RefSeq, Feb 2014]

Human, Mouse

-20°C or -80°C,2°C to 8°C

12352203