Western blot analysis of extracts of various cell lines using TDP-43/TARDB Polyclonal Antibody at 1:1000 dilution.
TARDBP Polyclonal Antibody
E-AB-60239
Product group Antibodies
Overview
- SupplierElabscience
- Product NameTARDBP Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionHIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
- UNSPSC12352203