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TAS-119

HY-137377
MedChem Express
CAS Number1453099-83-6
DownloadMSDS
Product group Chemicals
Estimated Purity98.03
Molecular Weight506.36
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Overview

  • Supplier
    MedChem Express
  • Product Name
    TAS-119 [1453099-83-6]
  • Delivery Days Customer
    10
  • CAS Number
    1453099-83-6
  • Certification
    Research Use Only
  • Estimated Purity
    98.03
  • Molecular Formula
    C23H22Cl2FN5O3
  • Molecular Weight
    506.36
  • Scientific Description
    TAS-119 is a potent, selective and orally active Aurora A inhibitor with an IC 50 of 1.0 nM. TAS-119 shows high selectivity for Aurora A over other protein kinases, including Aurora B ( IC 50 of 95 nM). TAS-119 has potent antitumor activites [1] .
  • SMILES
    O=C(C1(CC2=NC(NC3=NNC(C)=C3)=C(F)C=C2)CCN(C(C4=CC=CC(Cl)=C4Cl)=O)CC1)O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200