TAS-119 [1453099-83-6]

TargetMol Chemicals

TAS-119 [1453099-83-6]

9

1453099-83-6

Chemical

Research Use Only

TAS-119

98.69%

C23H22Cl2FN5O3

506.36

TAS-119 (TAS-2104) is an orally available, selective and potent inhibitor of Aurora A with an IC50 of 1.0 nM.TAS-119 also inhibits Aurora B with an IC50 of 95 nM.TAS-119 has a higher affinity for Aurora A than for Aurora B.TAS-119 exhibits potent antitumor activity and potential antimitotic activity. TAS-119 has potent anti-tumor activity and potential anti-mitotic activity.

3 years

Cc1cc(Nc2nc(CC3(CCN(CC3)C(=O)c3cccc(Cl)c3Cl)C(O)=O)ccc2F)n[nH]1

-20°C

12352200