TCF3 / E2A antibody, Internal

GeneTex

TCF3 / E2A antibody, Internal

9

WB: 0.01-0.03microg/ml. IHC-P: 3-5microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.50 mg/ml

Unconjugated

TCF3

transcription factor 3

AGM8, AGM8A, AGM8B, E2A, E47, ITF1, TCF-3, VDIR, bHLHb21, p75, transcription factor E2-alpha, E2A-HLF fusion transcript protein, NOL1-TCF3 fusion, VDR interacting repressor, class B basic helix-loop-helix protein 21, helix-loop-helix protein HE47, immunoglobulin transcription factor 1, kappa-E2-binding factor, negative vitamin D response element-binding protein, transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47), transcription factor ITF-1, vitamin D receptor-interacting repressor

Goat

IgG

Transcription factor E2-alpha

This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Sep 2011]

-20°C or -80°C,2°C to 8°C

12352203