TCF3 / E2A antibody [HL1954]

GeneTex

TCF3 / E2A antibody [HL1954]

9

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

HL1954

1 mg/ml

Unconjugated

TCF3

transcription factor 3

AGM8; bHLHb21; class B basic helix-loop-helix protein 21; E2A; E2A-HLF fusion transcript protein; E47; helix-loop-helix protein HE47; immunoglobulin transcription factor 1; ITF1; kappa-E2-binding factor; negative vitamin D response element-binding protein; NOL1-TCF3 fusion; p75; TCF-3; transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47); transcription factor 3 variant 3; transcription factor E2-alpha; transcription factor ITF-1; VDIR; VDR interacting repressor; vitamin D receptor-interacting repressor

Rabbit

IgG

This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Sep 2011]

Human

2°C to 8°C,-20°C or -80°C

12352203