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ProductsBack/TCP1 gamma antibody

GTX33073 ICC/IF Image

GTX33073 ICC/IF Image

GTX33073 ICC/IF Image

TCP1 gamma antibody

Research Use Only

GTX33073

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

DownloadDatasheet

Product group Antibodies

ReactivityHuman, Mouse

Overview

Supplier
GeneTex
Product Name
TCP1 gamma antibody
Delivery Days Customer
10
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Scientific Description
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants have been characterized for this gene. In addition, a pseudogene of this gene has been found on chromosome 8. [provided by RefSeq, Aug 2010]
Reactivity
Human, Mouse
Storage Instruction
2°C to 8°C,-20°C
UNSPSC
12352203

References

Chaperonin-Containing TCP-1 Promotes Cancer Chemoresistance and Metastasis through the AKT-GSK3beta-beta-Catenin and XIAP-Survivin Pathways. Chang YX et al., 2020 Dec 21, Cancers (Basel)
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