WB analysis of MCF7 lysate (30ug) using TDP1 antibody at a dilution of 1:1,000.
WB analysis of MCF7 lysate (30ug) using TDP1 antibody at a dilution of 1:1,000.
TDP1 antibody [AT1F2]
GTX53791
Overview
- SupplierGeneTex
- Product NameTDP1 antibody [AT1F2]
- Delivery Days Customer9
- Application Supplier NoteThe antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1000 ~ 2000. Recommended starting dilution is 1:1000.
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDAT1F2
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID55775
- Target nameTDP1
- Target descriptiontyrosyl-DNA phosphodiesterase 1
- Target synonymstyr-DNA phosphodiesterase 1; tyrosyl-DNA phosphodiesterase 1
- HostMouse
- IsotypeIgG2b
- Protein IDQ9NUW8
- Protein NameTyrosyl-DNA phosphodiesterase 1
- Scientific DescriptionThe protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). [provided by RefSeq, Aug 2016]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203