WB analysis of various sample lysates using GTX66457 TDP1 antibody. Dilution : 1:1000 Loading : 25microg per lane
WB analysis of various sample lysates using GTX66457 TDP1 antibody. Dilution : 1:1000 Loading : 25microg per lane
TDP1 antibody
GTX66457
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Rat
TargetTDP1
Overview
- SupplierGeneTex
- Product NameTDP1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:2000. ICC/IF: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID55775
- Target nameTDP1
- Target descriptiontyrosyl-DNA phosphodiesterase 1
- Target synonymstyr-DNA phosphodiesterase 1; tyrosyl-DNA phosphodiesterase 1
- HostRabbit
- IsotypeIgG
- Protein IDQ9NUW8
- Protein NameTyrosyl-DNA phosphodiesterase 1
- Scientific DescriptionThe protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). [provided by RefSeq, Aug 2016]
- ReactivityHuman, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203