![IHC-P analysis of human thymoma tissue using GTX04417 TdT antibody [MSVA-453R] HistoMAX?. Strong TdT immunostaining in a thymoma. IHC-P analysis of human thymoma tissue using GTX04417 TdT antibody [MSVA-453R] HistoMAX?. Strong TdT immunostaining in a thymoma.](https://www.genetex.com/upload/website/prouct_img/normal/GTX04417/GTX04417_20230728_IHC-P_115_23072722_225.webp)
IHC-P analysis of human thymoma tissue using GTX04417 TdT antibody [MSVA-453R] HistoMAX?. Strong TdT immunostaining in a thymoma.
TdT antibody [MSVA-453R] HistoMAX(tm)
GTX04417
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetDNTT
Overview
- SupplierGeneTex
- Product NameTdT antibody [MSVA-453R] HistoMAX(tm)
- Delivery Days Customer9
- Application Supplier NoteIHC-P: 1:75-1:150. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDMSVA-453R
- Concentration0.2 mg/ml
- ConjugateUnconjugated
- Gene ID1791
- Target nameDNTT
- Target descriptionDNA nucleotidylexotransferase
- Target synonymsTDT, DNA nucleotidylexotransferase, nucleosidetriphosphate:DNA deoxynucleotidylexotransferase, terminal addition enzyme, terminal deoxynucleotidyltransferase, terminal deoxyribonucleotidyltransferase, terminal transferase
- HostRabbit
- IsotypeIgG
- Protein IDP04053
- Protein NameDNA nucleotidylexotransferase
- Scientific DescriptionThis gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC41116161
![IHC-P analysis of human Merkel-cell carcinoma from skin tissue using GTX04417 TdT antibody [MSVA-453R] HistoMAX?. Merkel cell carcinoma with moderate to strong TdT immunostaining in > 80% of tumor cells. IHC-P analysis of human Merkel-cell carcinoma from skin tissue using GTX04417 TdT antibody [MSVA-453R] HistoMAX?. Merkel cell carcinoma with moderate to strong TdT immunostaining in > 80% of tumor cells.](https://www.genetex.com/upload/website/prouct_img/normal/GTX04417/GTX04417_20230728_IHC-P_245_23072722_789.webp)
![IHC-P analysis of human Merkel-cell carcinoma from skin tissue using GTX04417 TdT antibody [MSVA-453R] HistoMAX?. Merkel cell carcinoma with strong TdT positivity in < 5% of tumor cells. IHC-P analysis of human Merkel-cell carcinoma from skin tissue using GTX04417 TdT antibody [MSVA-453R] HistoMAX?. Merkel cell carcinoma with strong TdT positivity in < 5% of tumor cells.](https://www.genetex.com/upload/website/prouct_img/normal/GTX04417/GTX04417_20230728_IHC-P_375_23072723_257.webp)





![IHC-P analysis of human thymus tissue using GTX01873 TdT antibody [SEN28]. Note nuclear staining for cortical thymic lymphocytes.](https://www.genetex.com/upload/website/prouct_img/normal/GTX01873/GTX01873_20200811_IHC-P_82_w_23053121_940.webp)

![TdT antibody [C1C3] detects TdT protein by western blot analysis. A. 30 μg Jurkat whole cell extract B. 30 μg Jurkat nuclear extract 7.5 % SDS-PAGE TdT antibody [C1C3] (GTX108697) dilution: 1:500](https://www.genetex.com/upload/website/prouct_img/normal/GTX108697/GTX108697_41577_WB_Fraction_w_23060120_366.webp)