IHC-P analysis of human thymus tissue using GTX01873 TdT antibody [SEN28]. Note nuclear staining for cortical thymic lymphocytes.
IHC-P analysis of human thymus tissue using GTX01873 TdT antibody [SEN28]. Note nuclear staining for cortical thymic lymphocytes.
TdT antibody [SEN28]
GTX01873
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetDNTT
Overview
- SupplierGeneTex
- Product NameTdT antibody [SEN28]
- Delivery Days Customer9
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDSEN28
- ConjugateUnconjugated
- Gene ID1791
- Target nameDNTT
- Target descriptionDNA nucleotidylexotransferase
- Target synonymsDNA nucleotidylexotransferase; nucleosidetriphosphate:DNA deoxynucleotidylexotransferase; TDT; terminal addition enzyme; terminal deoxynucleotidyltransferase; terminal deoxyribonucleotidyltransferase; terminal transferase
- HostMouse
- IsotypeIgG2a
- Scientific DescriptionThis gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203